منابع مشابه
Fibrinogen in the Radioimmunoassay of Human Fibrinopeptide
A radioimmunoassay (RIA) technique has been devised for the measurement of human fibrinopeptide A (PA). The system utilizes rabbit antiserum to native human PA and a synthetic fibrinopeptide, with tyrosine substituted for phenylanine in amino acid position 8. The test detects native human PA at a concentration of 0.1 ng/ml, but does not cross react with human flbrinopeptide B or with flbnnopept...
متن کاملFibrinogen in the Radioimmunoassay of Human Fibrinopeptide A
A radioimmunoassay (RIA) technique has been devised for the measurement of human fibrinopeptide A (PA). The system utilizes rabbit antiserum to native human PA and a synthetic fibrinopeptide, with tyrosine substituted for phenylanine in amino acid position 8. The test detects native human PA at a concentration of 0.1 ng/ml, but does not cross react with human flbrinopeptide B or with flbnnopept...
متن کاملRadioimmunoassay of human fibrinopeptide B and kinetics of fibrinopeptide cleavage by different enzymes.
Thrombin converts fibrinogen to fibrin monomer by cleaving fibrinopeptides A and B (FPA and FPB) from the amino terminal ends of the A (alpha) and B (beta) chains. A radioimmunoassay capable of measuring the A peptide in human blood as an index of thrombin action in vivo has been described previously. This paper describes the development of a radioimmunoassay for FPB and the use of both assays ...
متن کاملReaction of plasmic degradation products of fibrinogen in the radioimmunoassay of human fibrinopeptide A.
A radioimmunoassay (RIA) technique has been devised for the measurement of human fibrinopeptide A (FPA). The system utilizes rabbit antiserum to native human FPA and a synthetic fibrinopeptide, with tyrosine substituted for phenylanine in amino acid position 8. The test detects native human FPA at a concentration of 0.1 ng/ml, but does not cross react with human fibrinopeptide B or with fibrino...
متن کاملMeasurement of fibrinopeptide A in human blood.
Since thrombin cleaves fibrinopeptides A (FPA) and B from the NH(2)-terminal end of the fibrinogen molecule, measurement of fibrinopeptide levels in plasma may provide a direct index of thrombin action. Recently a radioimmunoassay for FPA has been developed, and in the present paper, we describe the application of this assay to the measurement of FPA levels in clinical blood samples. Since fibr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1971
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.68.10.2350